每日一词Diffuseaxonali

Diffuseaxonalinjury(DAI)isabraininjuryinwhichscatteredlesionsoccuroverawidespreadareainwhitemattertractsaswellasgreymatter.DAIistheresultoftraumaticshearingforcesthatoccurwhentheheadisrapidlyacceleratedordecelerated,asmayoccurincaraccidents,falls,andassaults.Besidesmechanicalbreakingoftheaxonalcytoskeleton,DAIpathologyalsoincludessecondaryphysiologicalchangessuchasinterruptedaxonaltransport,progressiveswellingsanddegeneration.LesionstypicallyexistinthewhitematterofbrainsinjuredbyDAI;theselesionsvaryinsizefromabout1–15mmandaredistributedinacharacteristicway.DAImost

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